The prevalence of obesity is increasing globally. Despite the availability of a variety of\nanti-obesogenic drugs, including therapies under clinical development, these treatments are often\nindicated for patients with severe obesity, making them unsuitable for patients with mild obesity\nor for preventative use. In Thailand, traditional remedies employing medicinal plants are widely\nused to maintain health and treat disease. These treatments are generally inexpensive and readily\navailable at markets, making them good treatment options for preventing obesity. To evaluate the\nanti-obesogenic potential of Thai medicinal plants, we employed three in vitro methods: pancreatic\nlipase inhibition, lipolysis enhancement, and lipid accumulation reduction assays. Among 70 Thai\nmedicinal plants, Eurycoma longifolia Jack, Tiliacora triandra Diels, and Acacia concinna (Willd.) DC.\nwere selected as the most favorable candidates because they exhibited anti-obesogenic activity in all\nthree assays. These medicinal plants are expected to have effcient anti-obesogenic effects, making\nthem promising candidates for further study.
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